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DARP

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Diabetes Australia Research Program

Thanks to the generousity of our donors, Diabetes Victoria is one of the biggest funder of this national program. 

The Diabetes Australian Research Program (DARP) supports and develops outstanding diabetes research in Australia.

Diabetes Victoria is delighted the projects focus on all types of diabetes – including prevention, management and the search for a cure – all seeking to bring to an end the often devastating complications of this chronic condition.

The 2024 DARP grant

Victorian diabetes researchers have secured 10 funded research projects representing over 50 percent of the 2024 Diabetes Australia Research Program (DARP) national grant round. 

The funded projects are awarded to some of the brightest minds in diabetes research in Victoria and will aim to find new ways to prevent and treat diabetes and related complications. 
Diabetes Victoria is proud to make a significant contribution to the national DARP funding pool over many years. 

DARP supports and develops outstanding diabetes research in Australia by funding a range of grants across the full spectrum of diabetes research. The grants are available to non-profit organisations and recipients are selected through a merit-based peer review process. 

Among the recipients for the 2024 grant round is Professor Glenn Wadley of Deakin University, who is leading the development of a vitamin C treatment to aid the healing of foot ulcers in people with diabetes. An exercise physiologist with 25 years of research experience, Dr Wadley has a growing international reputation. The general grant he has secured will fund a clinical trial to provide the first strong evidence as to whether vitamin C supplementation can improve foot ulcer healing and if it will help to prevent some of the 4,400 amputations annually in Australia.

Dr Helena Qin of Monash University has secured the Millennium Type 2 Diabetes Award to fund her research project, which has the potential to revolutionise the treatment of kidney scarring (renal fibrosis) in people with diabetes. Dr Qin’s expertise in drug design means this new treatment strategy could ultimately reduce kidney-related diabetes complications and deaths. 

Dr Karen Alt of Monash University has secured a general grant for her project to find improved methods for detecting kidney scarring. Currently the only screening method is invasive biopsies – Dr Alt’s proposal will develop a non-invasive imaging method to identify and stage renal fibrosis in diabetes. 

2024 DARP recipients in Victoria

The 2024 DARP grant round received 193 applications, with 18 research projects selected for funding nation-wide. Read more about each project below.

Researcher 

Institute 

Project Title 

Charles Campbell Coghlan OAM Emerging Researcher Award 

Dr Steven James 

University of the Sunshine Coast 

The TREE study – Type 1 diabetes acRoss thE lifEspan  

Millennium Type 1 Diabetes Award 

Professor Anthony Russell 

Monash University 

A randomised controlled trial of plasmalyte versus normal saline as resuscitation and maintenance fluid therapy for patients presenting with diabetic ketoacidosis (BEST-DKA)BalancEd fluids vs Saline Trial in Diabetic KetoAcidosis 

Millennium Type 2 Diabetes Award 

Dr Chengxue (Helena) Qin 

Monash University 

A novel approach to treat diabetic kidney disease   

 

General Grants 

Researcher 

Institute 

Project Title 

Professor Karen Jones 

The University of Adelaide 

Utilising novel molecular imaging to quantify portal glucagon-like peptide-1 (GLP-1) receptor density in type 2 diabetes 

Professor Glenn Wadley 

Deakin University 

Vitamin C treatment to aid the healing of foot ulcers in people with diabetes: a randomised, placebo-controlled double-blind trial 

Distinguished Professor Tracy Levett-Jones 

University of Technology Sydney 

Enhancing healthcare professionals’ empathy skills in the provision of care for people living with or at risk of diabetes 

Professor Toby Coates 

The University of Adelaide 

The Development of Chimeric Antigen Receptor (CAR) T regulatory Cells as a Novel Therapy for Type 1 Diabetes 

Dr Sarah Turpin-Nolan 

Monash University 

Targeting gut ceramides – a new way to improve systemic insulin sensitivity 

Dr Miles De Blasio 

Monash Institute of Pharmaceutical Sciences (MIPS), Monash University 

Mitochondrial-targeted therapies to limit the structural and functional changes in diabetic cardiomyopathy 

Associate Professor Jonathan Oakhill 

St. Vincent’s Institute of Medical Research 

A smart, muscle-targeted drug-delivery system to combat type 2 diabetes 

Dr Andrew Fleetwood 

Baker Heart & Diabetes Institute 

Interferon-alpha links clonal haematopoiesis and atherosclerosis in diabetes 

Dr Karen Alt 

Monash University 

Translational Kidney Fibrosis Imaging in Diabetes 

Associate Professor Christina Bursill 

South Australian Health and Medical Research Institute 

Plaque-targeted Nrf2 activation to prevent diabetes-accellerated atherosclerosis using a novel switchable fumarate drug 

Dr Mahesh Umapathysivam 

University of Adelaide 

Do carriers of type 2 diabetes risk alleles in PAM have accelerated gastric emptying? 

Professor Leonie Heilbronn 

The University of Adelaide 

A randomised controlled trial comparing caloric restriction and meal timing on the circadian regulation of immune cells in individuals at high risk of type 2 diabetes. 

Dr Cong Xie 

The University of Adelaide 

Development of a novel bile acid-based therapy to optimise postprandial glycaemic control in type 2 diabetes 

Dr Patricia Rusu 

Monash University 

Deciphering the Nutritional and Neuronal Drivers of Protein Satiety 

Dr Phillip Kantharidis 

Monash University 

Targeting kidney macrophages as a novel treatment for diabetic kidney disease 

The 2023 DARP grant

New funding for Victorian researchers to find the next breakthrough in diabetes.

Victorian diabetes researchers have secured 14 innovative research projects representing 40 percent of the 2023 Diabetes Australia Research Program (DARP) grants.
 

Diabetes Victoria is delighted the projects focus on all types of diabetes – including prevention, management and the search for a cure – all seeking to bring to an end the often devastating complications of this chronic condition.

“Diabetes Victoria strives to support world class research in diabetes to further our understanding of this serious and complex condition. Every dollar spent on research is an important investment. Each research project funded may hold a vital key to that next breakthrough,” says Diabetes Victoria CEO, Glen Noonan.

Diabetes Victoria is a proud supporter of the Diabetes Australia Research Program (DARP).

“Since 1987, we have been a significant contributor to the DARP funding pool, supporting more than 350 diabetes research projects in Victoria. This includes contributing more than $19 million over the past decade alone,” Mr Noonan adds.

Research is critically important to help tackle the diabetes epidemic in Australia, with the number of people diagnosed continuing to grow in numbers and impact. Diabetes is a relentless condition to manage, requiring significant efforts every day to keep glucose levels within a safe range. This is to avoid both low and high glucose levels, which can cause serious short and long‐term complications, including coma, heart attack, stroke, vision loss, amputations and kidney damage.

“But it’s not just the physical impacts of diabetes that we are concerned about. Diabetes takes a toll on mental health. And every day, through our advocacy helpline, we hear that some people with diabetes still experience discrimination, e.g. in schools and workplaces, and many, many more face stigma in their everyday lives. Research is needed more than ever to improve both the health and quality of life of people with diabetes,” Mr Noonan says.

The 2023 DARP‐funded projects are seeking answers to a range of very diverse questions,
highlighting that diabetes is a complex condition that can impact almost every cell and organ in the body, and every aspect of a person’s life.

Among the researchers to receive funding is Dr John Karas. His study is seeking to develop a new oral form of insulin. He is trying to solve a problem that has plagued diabetes researchers for almost 100 years – the oral delivery of insulin as capsules or tablets. Scientists have struggled to make insulin as a pill, because insulin is unstable and degrades quickly in the body as soon as it is digested. This is why insulin is still given as an injection or via a continuous infusion by an insulin pump. All people with type 1 diabetes and around one quarter of people with type 2 diabetes need to inject insulin every day.

Another promising and DARP‐funded project is led by Dr Elizabeth Holmes‐Truscott from Deakin University and the Australian Centre for Behavioural Research in Diabetes (ACBRD). Dr Holmes‐Truscott seeks to investigate how negative perceptions around diabetes and diabetes stigma affect women with gestational diabetes. This type of diabetes is growing at a considerable rate, affecting one in six pregnancies. Dr Holmes‐Truscott’s work has already shown that stigma substantially adds to the burden of living with type 1 and type 2 diabetes. Now, with this new funding, she will be able to examine how it affects the emotional wellbeing, self‐care and outcomes of women with gestational diabetes.

The Victorian recipients of the 2023 DARP grants come from many of Melbourne’s most well‐known institutions including Monash University, the University of Melbourne, Deakin University, St Vincent’s Institute of Medical Research and Baker Heart & Diabetes Institute.

DARP 2023 Funded projects in Victoria

DARP 2023 funded projects

About diabetes in Victoria

We support, empower and campaign for all Victorians living with, or affected, by diabetes.

  • Every day, 90 Victorians develop diabetes… making it the fastest growing chronic condition in our state.
  • All types of diabetes are serious and can cause further health complications.
  • In Victoria, there are currently more than 383,000 Victorians registered with the National Diabetes Services Scheme.
  • The prevalence of type 2 diabetes is rising at an alarming rate. Every year, more than 17,000 Victorians develop type 2 diabetes. In addition, there are another 13,000 Victorian women with gestational diabetes who are at high risk of developing type 2 diabetes after their pregnancy.
  • Heart attacks and strokes are up to four times more likely in people with diabetes.
  • Diabetes is the leading cause of preventable blindness in adults.
  • Kidney failure is three times more common in people with diabetes.
  • Amputations are 15 times more common in people with diabetes.
  • Depression, anxiety and distress affect more than 30 per cent of all people with diabetes.
  • The full list of all DARP‐funded projects in Victoria is published below.
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