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Insulin

Insulin

Manufactured or human insulin is used in Australia. There are five different types of insulin. Each different type of insulin is different in its onset of action, peak and how long it can last for in the body.

 

Insulin types and their action

The strength of insulin used in Australia is 100 units per ml. In some countries overseas different strengths of insulin are available. Insulin is available in vials cartridges or pre-filled pens. Not all options are available with each type of insulinYour doctor or diabetes specialist will work out which insulin regimen is most suitable for your diabetes.

Ultra short acting analogues

  • Should be injected immediately before eating
  • Clear appearance
Onset: 5 to 15 min Peak: 1 to 3 hours Duration: 5 hours
Drug name Brand name Manufacturer
Insulin Aspart Novorapid Novo Nordisk
Insulin Lispro Humalog Eli Lilly
Insulin Glulisine Apidra Sanofi-Aventis

Short acting insulins

  • Should be injected half an hour before a meal
  • Clear appearance
Onset: 30 mins Peak:  2.5 to 5 hour Duration: 8 hours
Drug name Brand name Manufacturer
Insulin neutral (regular) Actrapid Novo Nordisk
Insulin neutral (regular) Humulin R Eli Lilly

Intermediate acting insulins

  • Does not need to be injected with a meal
  • Cloudy in appearance
  • Needs to be gently shaken before every use
Onset: 1.5 hrs Peak: 4 to 12 hrs Duration: 12 to 16 ( up to 24hrs)
Drug name Brand name Manufacturer
Isophane Protaphae Novo Nordisk
Isophane (NPH Humulin NPH Eli Lilly

Long acting analogue insulins

  • Clear in appearance
  • Does not need to be injected with a meal
Drug name Brand name Manufacturer
Insulin determir Levemir Novo Nordisk
Insulin glargine Lantus Sanofi-Aventis

Pre-mixed insulins

These insulins combine a mixture of two different types of insulin:

  • Cloudy in appearance
  • Should be gently shaken before every use
  • Humalog Mix and NovoMix need to be injected immediately before a meal
  • Mixtard and Humulin should be injected half an hour before a meal
Onset: varies Peak: varies  Duration: varies
Drug name Brand name Manufacturer
25 per cent insulin lispro/ 75 per cent insulin lispro protamine suspension
Humalog Mix 25 Eli Lilly
50 per cent insulin lispro/ 50 per cent insulin lispro protamine suspension Humalog Mix 50 Eli Lilly
30 per cent insulin aspart/ 70 per cent insulin aspart protamine supension NovoMix 30
Novo Nordisk
30 per cent insulin neutral (regular) 70 per cent isophane Humulin 30/70 Eli Lilly
30 per cent insulin neutral (regular) 70 per cent isophane
Mixtard 30/70 Novo Nordisk
50 per cent insulin neutral (regular) 50 per cent isophane Mixtard 50/50 Novo Nordisk
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